ogwu agwọ

Venom agwọ bụ mmiri mmiri nke agwọ na-egbu egbu na-ezopụta site na gland ha na-egbu egbu.Isi ihe mejupụtara ya bụ protein na-egbu egbu, na-aza 90% ruo 95% nke arọ akọrọ.Enwere ihe dị ka ụdị 20 nke enzymes na nsị.Na mgbakwunye, ọ nwekwara obere peptides molecular, amino acids, carbohydrates, lipids, nucleosides, amines biological and metal ion.Ngwakọta nke nsị agwọ dị nnọọ mgbagwoju anya, na nsị, nkà mmụta ọgwụ na toxicological mmetụta nke dị iche iche venoms agwọ nwere àgwà nke ha.N'ime ha, a na-egosi nsi ndị ahụ dị ka ndị a: 1. nsị na-ekesa ọbara: (gụnyere viper venom, agkistrodon acutus venom, caltrodon venom, venom green agwọ) 2. Neurotoxins: ( venom agwọ anya, mgbanaka ọla edo agwọ, ọla mgbanaka agwọ agwọ. , eze agwọ agwọ, venom rattlesnake) 3 Ngwakọta nsi: (Agkistrodon halys venom, Ophiodon halys venom) ① Mgbochi ọrịa cancer nke venom agwọ: ọrịa kansa bụ otu n'ime ọrịa atọ kachasị na-etinye ahụ ike mmadụ, ọ nweghị ọgwụgwọ dị irè na ugbu a.Ndị ọkà mmụta sayensị si mba niile na-ewere ọmụmụ banyere nsị agwọ dị ka ubi ọhụrụ iji merie ihe mgbochi a.Ụlọ ọrụ nyocha nke Snake Venom nke Mahadum Ahụike China na-agbalị ịchọta ihe ndị dị irè nke nwere ike igbochi uto tumor sitere na Agkistrodon halys venom nke a na-emepụta na Dalian, Liaoning, A na-eme nyocha mgbochi nke tumor n'etiti venom mbụ na venom dịpụrụ adịpụ nke Agkistrodon halys Pallas. .Ọnụ ọgụgụ itoolu dị iche iche nke venom agwọ nwere ogo dị iche iche nke mgbochi na sarcomas òké, na ọnụ ọgụgụ mgbochi tumor dị elu dịka 87.1%.Mmetụta anticoagulant nke venom agwọ: "defibrase" ewepụtara site na venom nke Agkistrodon halys acutus na Yunnan, China, gafere njirimara teknụzụ na 1981, ma jiri ya gwọọ ọrịa 333 nke thrombosis vaskụla, gụnyere ikpe 242 nke ụbụrụ ụbụrụ ụbụrụ, The Ọnụ ego dị irè bụ 86.4%.Agkistrodon halys antacid nke China Medical University na Shenyang Pharmaceutical College na mmekorita ya rụpụtara enwetala nsonaazụ ụlọ ọgwụ na-eju afọ n'ịgwọ ọrịa occlusive vaskụla.Antacid nke agwọ nke Snake Venom Research Office nke Mahadum Ahụike China mepụtara nwere ike ibelata lipids ọbara, gbasaa arịa ọbara, belata ọdịnaya nke thromboxane n'ọbara, mụbaa prostacyclin, ma mee ka ahụ dị nro vaskụla kwụsị.Ọ bụ ihe mgbochi dị mma.A na-akpọ ọgwụ a "reptilin injection".④ Nkwadebe nke serum antivenom: Mmepe nke serum antitivenom na China malitere na 1930s.Mgbe ntọhapụ gasịrị, ụlọ ọrụ Shanghai Institute of Biological Products, na nkwado nke Snake Research Group nke Zhejiang Medical University, Zhejiang Institute of Traditional Chinese Medicine, na Guangzhou Medical College, akwadola nke ọma nke ọma na-edozi antivenomi a nụchara anụcha maka Agkistrodon halys, Agkistrodon acutus. Bungarus multicinctus, na Ophthalmus.Mmetụta analgesic nke nsị agwọ: Na 1976, Yunnan Kunming Animal Research Institute rụpụtara nke ọma "Ketongling" site na venom nke venom agwọ, nke a na-eji agwọ ọrịa dị iche iche na-egbu mgbu ma nweta mmetụta analgesic pụrụ iche."Mkpokọta Ketongning" nke Cao Yisheng mepụtara egosila na ọ dị mma na ọgwụgwọ nke mgbu akwara, mgbu cancer na detoxification.N'ihi na analgesic venom agwọ nwere ọrụ analgesic dị elu ma ọ naghị eri ahụ, a na-eji ya dochie anya morphine na ọgwụgwọ mgbu mgbu cancer.Enwere ike iji venom nke venom iji dozie serum pụrụ iche na-egbochi venom, analgesics na hemostatic agents.Mmetụta ya dị mma karịa morphine na dolantin, ọ dịghịkwa eri ahụ.Venom agwọ nwekwara ike ịgwọ mkpọnwụ na polio.N'afọ ndị na-adịbeghị anya, a na-eji nsị agwọ gwọọ ọrịa kansa.N'ihi na nsị agwọ bụ ihe mejupụtara protein 34, otu n'ime ha dị oke mkpa na ọnụ ọgụgụ buru ibu nke nsị na-akpọ cytolysin.Ọ bụ nsí nke na-ebibi kpọmkwem mkpụrụ ndụ na akpụkpọ anụ.Nke a ga-emepụta etuto ọjọọ.Ọ bụrụ na ekewapụrụ cytolysin sitere na venom agwọ wee gbanye ya n'ime ahụ mmadụ ka ọ gbasaa n'ahụ niile site na mgbasa ọbara iji gbuo mkpụrụ ndụ kansa kpọmkwem, enwere nnukwu olileanya imeri ihe isi ike nke ọgwụgwọ ọrịa kansa.A na-ewepụta defibrase maka ịgba ntụtụ site na nsị nke Agkistrodon acutus na China.Ọ nwere ọrụ nke ibelata fibrinogen na thrombolysis, ọ bụkwa ọgwụ pụrụ iche maka ịgwọ ọrịa obi.Isi ihe asatọ a na-eji nsị agwọ bụ: 1. ọgwụgwọ ọrịa kansa na mgbochi ọrịa kansa, mgbochi tumor;2. Hemostasis na