Venom agwọ nwere ọtụtụ ihe na-eme ihe na-eme ndụ ndụ, ọkachasị gụnyere protease na polypeptide
Ọ bụ ihe dịka 90% ~ 95% nke arọ akọrọ nke venom agwọ [l
Site na mmepe nke teknụzụ na-aga n'ihu, ọtụtụ protein ndị na-emepụta ihe na-arụ ọrụ n'ime nsị agwọ na-eji nwayọọ nwayọọ
E kewapụrụ ya ma mee ka ọ dị ọcha, ndị mmadụ emewokwa ya
Mepụta nyocha miri emi na ya n'ebumnobi itinye ọgwụ ndị dị irè dị na nsị agwọ n'ahụ ndị mmadụ.
Na ọgwụgwọ nke ọrịa ndị yiri ya.Ugbu a, ihe ndị na-arụ ọrụ nke ọgwụ ndị dị irè dị na nsị agwọ
Nnyocha ọgwụ na ngwa ụlọ ọgwụ emere na-elekwasị anya na antithrombotic, hemostatic na hypoglycemic
Nrụgide, mgbochi ọrịa kansa na ihe mgbu.
L ọgwụ antithrombotic
Venom nke agwọ nwere mgbochi thrombotic na mmetụta thrombolytic gụnyere Ancelor
Enzyme (hoe crod), batmxobin, defibrase (de coerase) na Agkistrodon acutus.
Acutobin (enzyme).Atọ nke mbụ bụ nke snaI [e venom
Thmmbin dị ka enzynles, s Ⅷ.E), sVTLE bụ serine protease, otu ihe ahụ
O nwere arginine esterase na amidase ọrụ - 1. agwọ venom thrombin-dị ka enzyme.
Ọ na-arụ ọrụ na fibrinogen ịhapụ fibrinogen A ma ọ bụ B, ya mere
Ọ nwere ike imechi polymerization nke fibrin monomer isi na ọdụ, n'ihi na ọ na-egosi thrombin
Arụ ọrụ ma na-akpọ thrombin-dị ka.N'otu oge ahụ, agwọ venom thrombin-dị ka enzyme enweghị ike ịhụ n'ime mmadụ
Na-arụ ọrụ coagulation factor x Ⅲ na vivo, na fibrin monomer mepụtara site na hydrolysis ya.
Isi na ọdụ polymerization, mana enweghị ike ịmepụta njikọ njikọ njikọ n'akụkụ, nke dị mfe imebi sistemu reticuloendothelial eke.
A na-ebelata ọkwa plasma fibrinogen n'ihi phagocytosis ma ọ bụ mmebi site na usoro fibrinolytic.
Ọ nọ n'ọnọdụ fibrinolytic na-adịghị mma, ya mere ọ na-egosi anticoagulation na ịda mbà n'obi na ahụ
Fibrillation H1.Agkistrodon acutus enzyme bụ nke fibrinolytic enzyme, nke bụ fibrinolytic
Enwere ike kewaa mbiri nke enzyme [Erin (ogen) ol "icenzyme, FLE] n'ime otu yinye.
Zinc metalloproteinase na otu-agbụ ma ọ bụ okpukpu abụọ nke serine protease, ọkachasị akwa ọla zinc.
Enzyme ọcha.Agwọ venom fibrinolytic enzyme adịghị mkpa ịgbalite activator, na nwere ike bee kpọmkwem eriri.
Protein (protogen) na-emepụta hemofibrin, yabụ na ọ gaghị eme ka nchịkọta "J.
Site na nsị nke Agkistrodon halys (dịka sek, № r [md ∞ ka, ụgbọ mmiri) na Malaysia.
Ankylose dịpụrụ adịpụ bụ nke mbụ a na-eji na ọgwụgwọ ọgwụgwọ ọrịa thrombotic
ọgwụ SVTLE.6 J. Mgbe mmepe nke Ancelose gasịrị, ọtụtụ mba mụọ ya otu oge
Ndị nchọpụta kwenyere na sV'11E bụ ọgwụ kachasị mma maka ọgwụgwọ ọrịa thrombotic,
Na mgbakwunye na a na-eji ya maka ọgwụgwọ nke mpụta thrombosis, a pụkwara iji ya mee ihe maka ọgwụgwọ nke thrombosis miri emi na etiti venous thrombosis.
pulse thrombosis nwekwara mmetụta ọgwụgwọ "J.Site na 1990s, ọtụtụ mba na mpaghara
Qu Du nwere mmasị na ọgwụgwọ nke nnukwu ụbụrụ ischemia na ọrịa strok na aclase, na
Ọrụ ego: Sayensị ahụike agha na teknụzụ ndị ntorobịa ịzụlite teknụzụ (13QNP068);Ndị agha niile “12
5 "ọrụ nyocha ahụike izugbe (cwslJ280);Mpaghara ndị agha Chengdu "atụmatụ afọ ise nke iri na abụọ" nyocha ahụike
Ọrụ ndị dị mkpa (B12026);Ọrụ nyocha ahụike izugbe nke Chengdu Military Region n'oge atụmatụ afọ ise nke iri na abụọ
(C12062)
Ngalaba odee: 650032 Kunming, Chengdu Military Region Center for Disease Control and Prevention (Zhang Zhixiao,
Hu Tingsong, Cui Qinghua, Zheng Ying, Fan Quanshui);Pathogens, Ụlọ Akwụkwọ nke Ọgwụ Nkà na Ụzụ, Ụlọ Akwụkwọ Ọgwụ Ahụike Youjiang maka Mba
Ọfịs Nkuzi na Nchọpụta Ọdịnaya na Ọrịa Ọrịa (Xie Zhenfeng)
Onye edemede na-emekọrịta ihe: Fan Quanshui, E-mail: fqsl68@126 .com
Emeela ọtụtụ nyocha ngwa ụlọ ọgwụ dị obere.Ndekọ nyocha ojiji ọgwụ izizi
Na mgbakwunye, enwere ike iji Ancelose na ọgwụgwọ ụlọ ọgwụ nke ndị ọrịa nwere nnukwu ọrịa strok na mmalite mmalite
Ọ na-egosi mmetụta ọgwụgwọ dị mma.Mgbe nke ahụ gasịrị, ya na nnukwu kpuru ìsì okpukpu abụọ, nke placebo
Dị ka ụlọ ọgwụ ikpe, ọ, wdg N'ihi na 2613 ikpe nke nnukwu
Nsonaazụ ọgwụgwọ ọgwụ nke ndị ọrịa nwere ọrịa strok ischemic mmekọahụ gosipụtara na ndị ọrịa nọ na otu cloroxobin
Ọnụ ọgụgụ nlanarị ahụ abawanyela nke ukwuu, mana ihe ize ndụ nke hemorrhage intracranial abawanyela.Mgbe nke ahụ mechara
Nnwale ụlọ ọgwụ nke ndị ọrịa 1222 nwere nnukwu ọrịa strok ischemic gosipụtara na mgbe awa 3 gachara
A naghị atụ aro Ancelose maka ọgwụgwọ.1…. United States na Canada bipụtara na 2009
Ọrịa strok 500 metụtara mba na mpaghara 12 gụnyere Canada na Australia
na-ata ahụhụ
Oge nzipu: Feb-26-2023