Ebumnuche: Iji mụọ mmetụta nke Agkistrodon acutus venom tumor suppressor components I (AAVC-I) na mgbochi mgbasawanye na apoptosis nke mkpụrụ ndụ A549 cancer akpa ume mmadụ.Ụzọ: Ọnụego mgbochi nke AAVC-I na ntinye dị iche iche na sel A549 maka 24h na 48h ka a tụrụ ya site na usoro MTT;HE staining na Hoechst 33258 fluorescence staining na-eji na-ahụ apoptosis si morphology;Achọpụtara okwu nke protein bax site na immunohistochemistry.Nsonaazụ: MTT gosiri na AAVC-I nwere ike igbochi mmụba nke mkpụrụ ndụ A549 na oge na-adabere na usoro dose;Mgbe ọgwụgwọ AAVCI gasịrị maka awa 24, a na-ahụ pyknosis nuklia, hyperchromatic nuklia na ahụ apoptotic n'okpuru microscope;Immunohistochemistry gosipụtara na nkezi njupụta anya na-abawanye site na mmụba nke itinye uche ọgwụ, na-egosi na a na-ahazi ngosipụta nke protein bax n'otu aka ahụ.Mkpebi: Akụkụ Antitumor I nke Agkistrodon acutus venom nwere ike igbochi mkpụrụ ndụ cancer akpa ume mmadụ A549 ma mee ka apoptosis, nke nwere ike jikọta ya na nhazi elu nke okwu bax.
Oge nzipu: Jan-16-2023