Ebumnuche nke ikewapụ na sachaa protein anticoagulant site na Agkistrodon acutus venom dị na ndịda Anhui wee hụ mmetụta mgbochi ya na mkpụrụ ndụ endothelial vaskụla mmadụ.Ụzọ sel sel endothelial vaskụla mmadụ EC-304 ka emebere na vitro.Ejiri CCK-8 colorimetry chọpụta cytotoxicity nke akụkụ protein anticoagulant nke Agkistrodon halys venom na sel EC-304 mebere na vitro.A na-eji microscopy dị iche iche nke oge hụ mgbanwe dị na morphology cell na biochemistry nke mkpụrụ ndụ EC-304 nke a na-emeso ya na akụkụ protein anticoagulant nke Agkistrodon halys venom.Nsonaazụ Akụkụ protein anticoagulant nke Agkistrodon halys venom nwere mgbochi nke uto pụtara ìhè na mkpụrụ ndụ EC-304 (P μ Agụmakwụkwọ protein anticoagulant nke Agkistrodon halys venom (g/mL) nwere mmetụta mgbochi siri ike na sel EC-304, ọnụ ọgụgụ mgbochi ahụ mụbara. Site na mmụba nke dose ahụ, mkpụrụ ndụ EC-304 ejiri protein anticoagulant sitere na Agkistrodon halys venom gosipụtara mgbanwe morphological. Ọnụ ọgụgụ nke iberibe sel na usoro omenala abawanyela nke ukwuu.Mkpebi nke ntakiri protein anticoagulant nke Agkistrodon acutus venom sitere na ndịda Anhui Province nwere mmetụta mgbochi siri ike na sel EC-304, na ịkpata apoptosis nke sel EC-304 nwere ike ịbụ otu n'ime usoro ya.
Oge nzipu: Dec-29-2022