Mwakpo Antitumor na metastasis nke Agkistrodon acutus venom akụrụngwa ACTX-8 na ndịda Anhui Research na ọrụ

Ebumnuche iji nyochaa mmetụta na akụkụ nke akụrụngwa Agkistrodon acutus venom ACTX-8 na ntinye na mbuso agha nke cervical cancer cell Hela.

Sistemụ mmechi.Ụzọ Fibronectin dị na efere 96-nke ọma.Mkpụrụ ndụ Hela gafere 0, 2.5, 5, 10, 20, 40 g/ml nke ACTX-8

Mgbe ọgwụgwọ gasịrị, ahụrụ adhesion na Fibronectin, na ọnụ ọgụgụ nke sel ndị na-akwado ya bụ MTY;Nchọpụta mbuso agha cell na mbugharị site na usoro cell TransweU

Mgbanwe na ikike;Achọpụtara njikọ asọmpi n'etiti ACTX-8 na Fibronectin na Hela cell membrane site na cytometry eruba.Nsonaazụ:

Mgbe a gwọchara ya na ACTX-8, adhesion nke mkpụrụ ndụ Hela na Fibronectin belatara, nnwale nke mkpụrụ ndụ transwell gosiri na mkpụrụ ndụ Hela kwagara.

A na-ebelatakwa ikike nke ịkwaga na mbuso agha.Nsonaazụ cytometry eruba na-egosi na ACTX-8 nwere ike ịsọ mpi iji kechie onye na-anabata Fibronectin na sel.