Ngwa nke ogwu ogwu hemagglutinin

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Venom hemagglutinin, nke nwere thrombin na thrombin, ka ejirila ya mee ihe na hemostasis ụlọ ọgwụ n'ime afọ iri gara aga.Thrombin nwere ike ịkwalite nchịkọta platelet na saịtị ọbara ọgbụgba, na-akwalite mmebi nke fibrinogen, mepụta fibrin monomer, wee mee ka ọ ghọọ fibrin na-adịghị edozi, na-akwalite thrombosis na ebe ọbara ọgbụgba;Thrombin na-eme ka prothrombin na-arụ ọrụ ma na-eme ka mmepụta nke thrombin na-emepụta ngwa ngwa, si otú a na-eme ka usoro clotting dị mfe.

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Analgesia

Snake venom klas ọbara clotting enzyme nwere obere toxicity, na-arụ ọrụ ngwa ngwa (5 ~ 30 nkeji mgbe ọgwụgwọ nwere ike na-emepụta hemostatic mmetụta), irè ruo ogologo oge (mgbe ọrụ mmetụta na-adigide 48 ~ 72 awa) wdg, na ọtụtụ-eji na ụlọ ọgwụ mkpa. iji belata ọbara ọgbụgba ma ọ bụ ọnọdụ ọbara ọgbụgba (dị ka ịwa ahụ, ọgwụ ime ime, obstetrics na gynecology, ophthalmology, otolaryngology, hemorrhage oghere ọnụ na ọrịa hemorrhagic), Ọ nwekwara ike iji gbochie ọbara ọgbụgba (dịka ọmụmaatụ, ọgwụ tupu ịwa ahụ ahụ nwere ike izere ma ọ bụ belata ọbara ọgbụgba). na saịtị ịwa ahụ na mgbe ịwachara ahụ).Dị ka akwụkwọ akụkọ si kwuo, irè ọnụego agwọ venom hemagglutinin na ịwa ahụ mbepụ hemostasis na eriri afọ ọbara ọgbụgba dị nnọọ mma karịa nke phenolsulfonamides, sodium caroxesulfonate, vitamin K na ndị ọzọ hemostatic ọgwụ.

Ngwunye agwọ na-egbubu hemagglutinin nke a na-erebu n'ahịa na-agụnye ọgwụ mgbochi hemagglutinin agwọ (aha ahia: Sulejuan), agwọ venom hemagglutinin injections (aha ahia: Bangting), agkistrodon halys hemagglutinin injection (aha ahia: Otú ọ dị, nyocha usoro gosiri na ọ dịghị ihe ọ bụla. dị ịrịba ama dị iche iche na hemostatic arụmọrụ na omume nke ọjọọ mmeghachi omume n'etiti agwọ atọ.

Agwọ venom klas ọbara clotting enzyme bụ nkwadebe ndu, site na usoro kemịkalụ, bụ nke protein heterologous, yana mkpụrụ ndụ mast na vivo ma ọ bụ mkpụrụ ndụ basophilic cell, usoro mmeghachi omume na cell, ihe na-arụ ọrụ vaskụla, dị ka mwepụta histamine, ihe na-eme ngwa ngwa, ụdị Ⅰ mmetụta nfụkasị ahụ na ahụ, nwekwara ike jikọta ya na enzyme nwere adịghị ọcha.N'otu oge ahụ, ma trauma ịwa ahụ na mgbu na-esochi ya nwere ike iduga mmeghachi omume nke nnukwu oge (APR), dị ka mmụba nke ahụ ọkụ, ụba glucose ọbara, ịba ụba catabolism, nguzozi nitrogen na-adịghị mma na ịba ụba protein protein (APP).N'oge a iji nye protein allogenic, ahụ na-enwekarị ihe nfụkasị ahụ, ma ọ bụ ọbụna mmeghachi ahụ nfụkasị siri ike.Zhao Shanshan et al.nyochara akwụkwọ akụkọ gbasara mmeghachi omume ọjọọ nke ogwu ogwu hemagglutinase agwọ, wee chọpụta na 57 n'ime 69 nke mmeghachi omume ọjọọ mere n'ime otu elekere mgbe ịgba ọgwụ mgbochi ahụ gasịrị, 35 n'ime ha mere n'ime 1 ~ 5 nkeji mgbe ịgba ọgwụ mgbochi ahụ gasịrị.Mmeghachi omume nfụkasị ahụ na-amalite ngwa ngwa, ọ bụrụ na achọpụtara ya n'oge ma ọ bụ njikwa na-ekwesịghị ekwesị, mmepe ngwa ngwa nke ọrịa ahụ na ihe dị ize ndụ, ga-ebute nsonaazụ ọjọọ nye ndị ọrịa.

Ya mere, ekwesịrị iji nlezianya chịkwaa ihe ngosi na iji ọgwụ eme ihe, na akụkọ ahụike onye ọrịa, akụkọ ihe mere eme ọgwụ, akụkọ ihe mere eme nke allergies na akụkọ ihe mere eme ezinụlọ kwesịrị iji nlezianya jụọ tupu ojiji mbụ.Kwadebe ọgwụ na ihe ndị achọrọ maka ọgwụgwọ mberede tupu ejiri ya.Ọsọ ịgba ntụtụ kwesịrị ịdị nwayọ, yana ihe ịrịba ama dị mkpa nke ndị ọrịa na mgbanwe ndị ọzọ kwesịrị ka a hụ nke ọma na mmalite ọgwụ.Mgbe nyochachara nke ọma ruo ọtụtụ nkeji, ndị ọrịa nwere ike ịpụ iji hụ na enweghị mmeghachi omume ọjọọ.